SCOPE AND LIMITATIONS OF EXPLOITING THE ABILITY OF THE CHEMOSENSITIZER NV716 TO ENHANCE THE ACTIVITY OF TETRACYCLINE DERIVATIVES AGAINST PSEUDOMONAS AERUGINOSA

Scope and Limitations of Exploiting the Ability of the Chemosensitizer NV716 to Enhance the Activity of Tetracycline Derivatives against Pseudomonas aeruginosa

The spread of antibiotic resistance is an urgent threat to global health that requires new therapeutic approaches.Treatments for pathogenic Gram-negative bacteria are particularly challenging to identify due to the robust OM permeability barrier in these organisms.One strategy is to use antibiotic adjuvants, a class of drugs that have no significan

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Epigenome-wide association study and network analysis for IgA Nephropathy from CD19+ B-cell in Chinese Population

IgA nephropathy (IgAN) is the most common primary glomerular disease in China and worldwide.The proliferation of B cells is known to be associated with both risk and prognosis of IgAN, but the epigenetic mechanism underlying this association is unknown.In this study we carried out the first Epigenome-wide Association Study (EWAS) by using the lates

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